YWHAB monoclonal antibody, clone J2E9
产品名称： YWHAB monoclonal antibody, clone J2E9
英文名称： YWHAB monoclonal antibody, clone J2E9
产品编号： MAB3207
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant YWHAB.
- Immunogen:
- Recombinant protein corresponding to full length human YWHAB.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- 14-3-3 regulation of cell spreading and migration requires a functional amphipathic groove.
Rodriguez LG, Guan JL.J Cell Physiol. 2005 Jan;202(1):285-94.
- 2.
- Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase.
Mils V, Baldin V, Goubin F, Pinta I, Papin C, Waye M, Eychene A, Ducommun B.Oncogene. 2000 Mar 2;19(10):1257-65.
- Applications
- Western Blot (Cell lysate)
- Cell lysates of HeLa (30 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with YWHAB monoclonal antibody, clone J2E9 (Cat # MAB3207 ; 1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 7529
- Protein Accession#:
- NP_003395
- Gene Name:
- YWHAB
- Gene Alias:
- GW128,HS1,KCIP-1
- Gene Description:
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
- Omim ID:
- 601289
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq
- Other Designations:
- 14-3-3 protein beta/alpha,OTTHUMP00000031075,OTTHUMP00000031076,brain protein 14-3-3, beta isoform,protein 1054,protein kinase C inhibitor protein-1
- Gene Pathway
- Related Disease