HUS1 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： HUS1 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： HUS1 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00003364-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human HUS1 protein.
- Immunogen:
- HUS1 (NP_004498.1, 1 a.a. ~ 280 a.a) full-length human protein.
- Sequence:
- MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVELLSMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHLVIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQFLAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPALS
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of HUS1 expression in transfected 293T cell line (H00003364-T01) by HUS1 MaxPab polyclonal antibody.
Lane 1: HUS1 transfected lysate(31.70 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3364
- GeneBank Accession#:
- NM_004507
- Protein Accession#:
- NP_004498.1
- Gene Name:
- HUS1
- Gene Alias:
- -
- Gene Description:
- HUS1 checkpoint homolog (S. pombe)
- Omim ID:
- 603760
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq
- Other Designations:
- HUS1 checkpoint protein,hus1+-like protein