LRAT polyclonal antibody
产品名称： LRAT polyclonal antibody
英文名称： LRAT polyclonal antibody
产品编号： PAB17348
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LRAT.
- Immunogen:
- A synthetic peptide corresponding to internal of human LRAT.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody detects endogenous levels of total LRAT protein.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Mutations in the gene encoding lecithin retinol acyltransferase are associated with early-onset severe retinal dystrophy.
Thompson DA, Li Y, McHenry CL, Carlson TJ, Ding X, Sieving PA, Apfelstedt-Sylla E, Gal A.Nat Genet. 2001 Jun;28(2):123-4.
- 2.
- Lecithin retinol acyltransferase contains cysteine residues essential for catalysis.
Mondal MS, Ruiz A, Bok D, Rando RR.Biochemistry. 2000 May 2;39(17):5215-20.
- 3.
- Molecular and biochemical characterization of lecithin retinol acyltransferase.
Ruiz A, Winston A, Lim YH, Gilbert BA, Rando RR, Bok D.J Biol Chem. 1999 Feb 5;274(6):3834-41.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from COLO 205 cells, using LRAT polyclonal antibody (Cat # PAB17348).
Peptide "+" means "with peptide blocking".
- Entrez GeneID:
- 9227
- Protein Accession#:
- O95237
- Gene Name:
- LRAT
- Gene Alias:
- MGC33103
- Gene Description:
- lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
- Omim ID:
- 604863
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester, an essential reaction for the retinoid cycle in visual system and vitamin A status in liver. Mutations in this gene have been associated with early-onset severe retinal dystrophy. [provided by RefSeq
- Other Designations:
- lecithin retinol acyltransferase
- Gene Pathway