ANPEP monoclonal antibody, clone WM15 (PE)
产品名称： ANPEP monoclonal antibody, clone WM15 (PE)
英文名称： ANPEP monoclonal antibody, clone WM15 (PE)
产品编号： MAB4356
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ANPEP.
- Immunogen:
- Native purified ANPEP from human AML cell.
- Host:
- Mouse
- Theoretical MW (kDa):
- 150
- Reactivity:
- Human, Non-Human Primates
- Specificity:
- This antibody recognizes the human CD13 cell surface glycoprotein, a 150 KDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
- Form:
- Liquid
- Conjugation:
- PE
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- CD13 (GP150; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated.
Favaloro EJ, Browning T, Facey D.Exp Hematol. 1993 Dec;21(13):1695-701.
- 2.
- Myeloid progenitor surface antigen identified by monoclonal antibody.
Bradstock KF, Favaloro EJ, Kabral A, Kerr A, Hughes WG, Musgrove E.Br J Haematol. 1985 Sep;61(1):11-20.
- 3.
- Human myeloid differentiation antigens identified by monoclonal antibodies: expression on leukemic cells.
Bradstock KF, Favaloro EJ, Kabral A, Kerr A, Hughes WG, Berndt MC, Musgrove E.Pathology. 1985 Jul;17(3):392-9.
- Application Image
- Immunohistochemistry (Frozen sections)
- Immunoprecipitation
- Functional Study
- Flow Cytometry
- Entrez GeneID:
- 290
- Gene Name:
- ANPEP
- Gene Alias:
- APN,CD13,LAP1,PEPN,gp150,p150
- Gene Description:
- alanyl (membrane) aminopeptidase
- Omim ID:
- 151530
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq
- Other Designations:
- OTTHUMP00000194690,aminopeptidase M,aminopeptidase N,membrane alanine aminopeptidase,microsomal aminopeptidase