CDC14A (Human) Recombinant Protein (Q01)
产品名称: CDC14A (Human) Recombinant Protein (Q01)
英文名称: CDC14A (Human) Recombinant Protein (Q01)
产品编号: H00008556-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Human CDC14A partial ORF ( NP_003663, 431 a.a. - 530 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- PFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPE
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8556
- GeneBank Accession#:
- NM_003672
- Protein Accession#:
- NP_003663
- Gene Name:
- CDC14A
- Gene Alias:
- cdc14,hCDC14
- Gene Description:
- CDC14 cell division cycle 14 homolog A (S. cerevisiae)
- Omim ID:
- 603504
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- CDC10 (cell division cycle 10, S. cerevisiae, homolog),CDC14 homolog A,OTTHUMP00000012653,OTTHUMP00000012654,OTTHUMP00000012655,dual specificity protein phosphatase CDC14A
- Gene Pathway