RPSA monoclonal antibody, clone 33
产品名称： RPSA monoclonal antibody, clone 33
英文名称： RPSA monoclonal antibody, clone 33
产品编号： MAB9943
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant RPSA.
- Immunogen:
- Recombinant protein corresponding to full length human RPSA.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- It can expression in HeLa whole cell lysate.
- Form:
- Liquid
- Purification:
- Affinity purification
- Isotype:
- IgG2a
- Storage Buffer:
- In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western blot (1:1000)
The optimal working dilution should be determined by the end user.
- Entrez GeneID:
- 3921
- GeneBank Accession#:
- NM_002295.4
- Protein Accession#:
- NP_002286.2
- Gene Name:
- RPSA
- Gene Alias:
- 37LRP,67LR,LAMBR,LAMR1,LRP,p40
- Gene Description:
- ribosomal protein SA
- Omim ID:
- 150370
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- 67kD, ribosomal protein SA,laminin receptor 1 (67kD, ribosomal protein SA)
- Gene Pathway