FITC标记的钙磷蛋白1抗体
产品名称： FITC标记的钙磷蛋白1抗体
英文名称： Anti-Calcyphosine 1/FITC
产品编号： HZ-12161R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Calcyphosine 1/FITC Conjugated antibody
FITC标记的钙磷蛋白1抗体
| 英文名称 | Anti-Calcyphosine 1/FITC |
| 中文名称 | FITC标记的钙磷蛋白1抗体 |
| 别 名 | Calcyphosin; Calcyphosine 1; Calcyphosine; CAPS; CAPS1; CAYP1_HUMAN; Thyroid protein p24. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 21kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Calcyphosine 1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: CAPS1 is a 189 amino acid cytoplasmic protein that contains four EF-hand domains, which serve as calcium-binding sites, and was first identified in canine thyroid. Interestingly, CAPS1 is much less abundant in humans than in canines. Synthesis and phosphorylation of CAPS1 is upregulated by cAMP-agonists in thyrocytes. CAPS1 likely functions in the regulation of ionic transport and may be involved in cross-signaling between cAMP and Ca(+2)-phophatidylinositol cascades. In addition to thyriod, CAPS1 is expressed in brain, salivary glands and lung. Expression of CAPS1 is increased in endometrial cancer and prognosis seems to be dependent on the level of CAPS1 expression, indicating that CAPS1 may be an appropriate prognostic marker for patient survival. Function: Calcium-binding protein. May play a role in cellular signaling events. Subunit: Monomer. Does not form oligomers in the presence of calcium. Subcellular Location: Cytoplasm. Similarity: Contains 4 EF-hand domains. Database links: Entrez Gene: 828 Human Omim: 114212 Human SwissProt: Q13938 Human Unigene: 584744 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CAPS1是一种189个氨基酸的细胞质蛋白，包含四个EF-hand结构域，作为钙结合位点，首次在犬甲状腺中被鉴定。有趣的是，CAPs1在人类中的含量远低于犬科动物。CAPs1的合成和磷酸化通过cAMP激动剂在甲状腺细胞中上调。CAPS1可能在调节离子转运中起作用，并可能参与cAMP与Ca(+2)-磷酸肌醇级联之间的交叉信号传导。除了甲状腺激素外，CAPs1还可在脑、唾液腺和肺组织中表达。CAPS1在子宫内膜癌中的表达增加，其预后似乎取决于CAPS1表达的水平，表明CAPS1可能是患者生存的一个合适的预后标志物。