FITC标记的巨噬细胞炎性蛋白19抗体
产品名称： FITC标记的巨噬细胞炎性蛋白19抗体
英文名称： Anti-CCL19/FITC
产品编号： HZ-2454R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-CCL19/FITC Conjugated antibody
FITC标记的巨噬细胞炎性蛋白19抗体
| 英文名称 | Anti-CCL19/FITC |
| 中文名称 | FITC标记的巨噬细胞炎性蛋白19抗体 |
| 别 名 | Macrophage Inflammatory Protein 3β; ;Macrophage Inflammatory Protein 3 beta; Beta chemokine exodus 3; C C chemokine ligand 19; CC chemokine ligand 19; CCL19; Chemokine (C C motif) ligand 19; Chemokine (CC motif) ligand 19; Chemokine CC Motif Ligand 19; CK beta 11; CKb11; EBI1 ligand chemokine; ELC; Exodus 3; MGC34433; MIP 3 beta; MIP3 beta; MIP3B; OTTHUMP00000000531; SCYA19; Small inducible cytokine A19; CCL19_MOUSE. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 自然杀伤细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 9.2kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CCL19 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Jul 2008] Function: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Specifically binds to chemokine receptor CCR7. Subcellular Location: Secreted. Tissue Specificity: Highly expressed by dendritic cells in mesenteric and peripheral lymph nodes. Significant expression in spleen (T cell zone or periarteriolar lymphatic sheath) and Peyer patches. Low expression in thymus. Similarity: Belongs to the intercrine beta (chemokine CC) family. Database links: Entrez Gene: 6363 Human Entrez Gene: 100039053 Mouse Entrez Gene: 24047 Mouse Omim: 602227 Human SwissProt: Q99731 Human SwissProt: O70460 Mouse Unigene: 50002 Human Unigene: 426373 Mouse Unigene: 441169 Mouse Unigene: 459263 Mouse Unigene: 6660 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是在9号染色体的P臂上聚集的几种CC细胞因子基因之一。细胞因子是一类参与免疫调节和炎症过程的分泌蛋白家族。CC细胞因子是由两个相邻半胱氨酸表征的蛋白质。该基因编码的细胞因子可能在正常淋巴细胞再循环和归巢中发挥作用。在胸腺T细胞和T细胞和B细胞向次级淋巴器官的迁移中也起着重要的作用。它特异性结合趋化因子受体CCR7。[ RefSeq，JUL 2008 ]