PRKAG2 (Human) Recombinant Protein (Q01)
产品名称: PRKAG2 (Human) Recombinant Protein (Q01)
英文名称: PRKAG2 (Human) Recombinant Protein (Q01)
产品编号: H00051422-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PRKAG2 partial ORF ( AAH20540, 191 a.a. - 300 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- AFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAE
- Theoretical MW (kDa):
- 37.73
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 51422
- GeneBank Accession#:
- BC020540
- Protein Accession#:
- AAH20540
- Gene Name:
- PRKAG2
- Gene Alias:
- AAKG,AAKG2,CMH6,H91620p,WPWS
- Gene Description:
- protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- Gene Ontology:
- Hyperlink
- Gene Summary:
- AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- AMP-activated protein kinase gamma2 subunit,AMPK gamma2
- Related Disease
- Atherosclerosis
- Calcinosis
- Cardiomegaly
- Cardiomyopathy, Dilated
- Cardiomyopathy, Hypertrophic, Familial
- Cardiovascular Diseases
- Colonic Neoplasms
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Drug Toxicity
- Edema
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Insulin Resistance
- Kidney Failure, Chronic
- Rectal Neoplasms
- Tobacco Use Disorder