DOK5 polyclonal antibody
产品名称： DOK5 polyclonal antibody
英文名称： DOK5 polyclonal antibody
产品编号： PAB3411
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of DOK5.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human DOK5.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5.
Cai D, Dhe-Paganon S, Melendez PA, Lee J, Shoelson SE.J Biol Chem. 2003 Jul 11;278(28):25323-30. Epub 2003 May 1.
- 2.
- DOK4 and DOK5: new Dok-related genes expressed in human T cells.
Favre C, Gerard A, Clauzier E, Pontarotti P, Olive D, Nunes JA.Genes Immun. 2003 Jan;4(1):40-5.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of mouse cerebellum tissue lysate (35 ug/lane) with DOK5 polyclonal antibody (Cat # PAB3411).
- Entrez GeneID:
- 55816
- Protein Accession#:
- NP_060901;Q9P104
- Gene Name:
- DOK5
- Gene Alias:
- C20orf180,MGC16926
- Gene Description:
- docking protein 5
- Omim ID:
- 608334
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP. [provided by RefSeq
- Other Designations:
- OTTHUMP00000031322,downstream of tyrosine kinase 5