CCNT1 polyclonal antibody
产品名称： CCNT1 polyclonal antibody
英文名称： CCNT1 polyclonal antibody
产品编号： PAB9999
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CCNT1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human CCNT1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:1000-1:5000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Binding of CDK9 to TRAF2.
MacLachlan TK, Sang N, De Luca A, Puri PL, Levrero M, Giordano A.J Cell Biochem. 1998 Dec 15;71(4):467-78.
- 2.
- CDK9 (PITALRE): a multifunctional cdc2-related kinase.
de Falco G, Giordano A.J Cell Physiol. 1998 Dec;177(4):501-6.
- 3.
- Cloning of murine CDK9/PITALRE and its tissue-specific expression in development.
Bagella L, MacLachlan TK, Buono RJ, Pisano MM, Giordano A, De Luca A.J Cell Physiol. 1998 Nov;177(2):206-13.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical staining with CCNT1 polyclonal antibody (Cat # PAB9999) was diluted 1 : 500 to detect CCNT1 in human skin tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 904
- Gene Name:
- CCNT1
- Gene Alias:
- CCNT,CYCT1
- Gene Description:
- cyclin T1
- Omim ID:
- 602506
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit. [provided by RefSeq
- Other Designations:
- CDK9-associated C-type protein,cyclin C-related protein,cyclin T1b,subunit of positive elongation transcription factor b
- Related Disease