RASA3 polyclonal antibody
产品名称: RASA3 polyclonal antibody
英文名称: RASA3 polyclonal antibody
产品编号: PAB6714
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of RASA3.
- Immunogen:
- A synthetic peptide corresponding to human RASA3.
- Sequence:
- C-QYKRDKFKKTKYGSQ
- Host:
- Goat
- Theoretical MW (kDa):
- 95.7
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach.
Kuai J, Wooters J, Hall JP, Rao VR, Nickbarg E, Li B, Chatterjee-Kishore M, Qiu Y, Lin LL.J Biol Chem. 2004 Dec 17;279(51):53266-71. Epub 2004 Oct 13.
- Application Image
- ELISA
- Entrez GeneID:
- 22821
- Protein Accession#:
- NP_031394
- Gene Name:
- RASA3
- Gene Alias:
- GAP1IP4BP,GAPIII,MGC46517,MGC47588
- Gene Description:
- RAS p21 protein activator 3
- Omim ID:
- 605182
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq
- Other Designations:
- GTPase activating protein III,Ins(1,3,4,5)P4-binding protein,inositol 1,3,4,5-tetrakisphosphate-binding protein