HSPA8 Pre-design Chimera RNAi
产品名称: HSPA8 Pre-design Chimera RNAi
英文名称: HSPA8 Pre-design Chimera RNAi
产品编号: H00003312-R02
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Homo sapiens heat shock 70kDa protein 8 (HSPA8), transcript variant 2, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_153201
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 3312
- Gene Name:
- HSPA8
- Gene Alias:
- HSC54,HSC70,HSC71,HSP71,HSP73,HSPA10,LAP1,MGC131511,MGC29929,NIP71
- Gene Description:
- heat shock 70kDa protein 8
- Omim ID:
- 600816
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date. [provided by RefSeq
- Other Designations:
- LPS-associated protein 1,N-myristoyltransferase inhibitor protein 71,constitutive heat shock protein 70,heat shock 70kD protein 8,heat shock 70kd protein 10,heat shock cognate protein 54,heat shock cognate protein, 71-kDa,lipopolysaccharide-associated pro
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aneurysm, Dissecting
- Aortic Aneurysm, Thoracic
- Asthma
- Asthma
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Cognition
- Coronary Disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Infant, Premature, Diseases
- Kidney Failure, Acute
- Kidney Failure, Chronic
- Lung Neoplasms
- Metabolic Syndrome X