FITC标记的磷酸化丙氨酸蛋白激酶C底物Marcks抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的磷酸化丙氨酸蛋白激酶C底物Marcks抗体

FITC标记的磷酸化丙氨酸蛋白激酶C底物Marcks抗体

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产品名称： FITC标记的磷酸化丙氨酸蛋白激酶C底物Marcks抗体

英文名称： Anti-Phospho-MARCKS(Ser170)/FITC

产品编号： HZ-5500R-FITC

产品价格： null

产品产地： 中国/上海

品牌商标： HZbscience

更新时间： 2023-08-17T10:24:20

使用范围： IF=1:50-200

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 Rabbit Anti-Phospho-MARCKS(Ser170)/FITC Conjugated antibody

FITC标记的磷酸化丙氨酸蛋白激酶C底物Marcks抗体

 

英文名称 Anti-Phospho-MARCKS(Ser170)/FITC
中文名称 FITC标记的磷酸化丙氨酸蛋白激酶C底物Marcks抗体
别    名 80 kDa protein; 80K L; 80K L protein; 80K-L protein; 80KL; 81 kDa protein, light chain; light chain; MACS; MARCKS; MARCS; MARCS_HUMAN; MGC52672; myristoylated alanine rich C kinase substrate; Myristoylated alanine rich protein kinase C substrate (MARCKS, 80K L); Myristoylated alanine rich protein kinase C substrate; Myristoylated alanine-rich C-kinase substrate; Phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein light chain; Protein kinase C substrate.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 心血管  免疫学  信号转导  激酶和磷酸酶  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human MARCKS around the phosphorylation site of Ser170
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
MARCKS, (Myristoylated Alanine-Rich C Kinase Substrate), is a member of a family of calmodulin binding proteins and is a major substrate for phosphorylation by protein kinase C (PKC). The phosphorylation of Ser152/156 can be used as a measure of PKC activation. Phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin.

Function:
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.

Subcellular Location:
Cytoplasm, cytoskeleton (Probable). Membrane; Lipid-anchor.

Post-translational modifications:
Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.

Similarity:
Belongs to the MARCKS family.

Database links:
UniProtKB/Swiss-Prot: P29966.4

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

MARCKS是一种分子量为32kDa的膜内蛋白,在组织中广泛表达,但主要高表达在脑内的轴突、小直径的树突和树突棘

马尔克斯（肉豆蔻酰化富含丙氨酸的C激酶底物）是钙调素结合蛋白家族的成员，是蛋白激酶C（PKC）磷酸化的主要底物。Ser152／156的磷酸化可作为PKC活化的测量。Ser152／156的磷酸化调节马尔克斯与钙调素的结合。