RYBP抗体-第二抗体-抗体-生物在线
上海信裕生物科技有限公司
RYBP抗体

RYBP抗体

商家询价

产品名称： RYBP抗体

英文名称： RYBPAntibody

产品编号： XY 11365-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 RYBP抗体Applications

In-house applications ELISA, WB, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 11365-1-AP;K-562 cellsK-562 cells were subjected to SDS PAGE followed by western blot with 11365-1-AP(RYBP antibody) at dilution of 1:500
  • 11365-1-AP;mouse spleen tissueIP Result of anti-RYBP (IP:11365-1-AP, 4ug; Detection:11365-1-AP 1:300) with mouse spleen tissue lysate 4000ug.
Positive WB detected in K-562 cells
Positive IP detected in Mouse spleen tissue
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:1000
 RYBP抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
 RYBP抗体
Immunogen RYBP fusion protein ag1908 Full name RING1 and YY1 binding protein
Calculated molecular
weight		 228aa,25 kDa Observed molecular 
weight		 32 kDa
GenBank accession 
number		 BC014959 Gene ID (NCBI) 23429
Gene symbol RYBP Synonyms AAP1, APAP 1, Apoptin associating protein 1, DED associated factor, DEDAF, RING1 and YY1 binding protein, RYBP, YEAF1
Background

Polycomb repressive complexes (PRCs) are important chromatin regulators of embryonic stem (ES) cell function [PMID:22269950]. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B and has been suggested to assist PRC localization to their targets. RYBP, firstly identified as a direct interactor with Ring1A, acts as transcriptional repressor in reporter assays, both in tissue culture cells and in the fly [PMID:16125914] RYBP抗体

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