STRADB polyclonal antibody
产品名称： STRADB polyclonal antibody
英文名称： STRADB polyclonal antibody
产品编号： PAB2653
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of STRADB.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human STRADB.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase.
Nishigaki K, Thompson D, Yugawa T, Rulli K, Hanson C, Cmarik J, Gutkind JS, Teramoto H, Ruscetti S.J Biol Chem. 2003 Apr 11;278(15):13520-30. Epub 2003 Feb 6.
- 2.
- ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis.
Sanna MG, da Silva Correia J, Luo Y, Chuang B, Paulson LM, Nguyen B, Deveraux QL, Ulevitch RJ.J Biol Chem. 2002 Aug 23;277(34):30454-62. Epub 2002 Jun 4.
- 3.
- Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2.
Hadano S, Yanagisawa Y, Skaug J, Fichter K, Nasir J, Martindale D, Koop BF, Scherer SW, Nicholson DW, Rouleau GA, Ikeda J, Hayden MR.Genomics. 2001 Jan 15;71(2):200-13.
- Entrez GeneID:
- 55437
- Protein Accession#:
- NP_061041;Q9C0K7
- Gene Name:
- STRADB
- Gene Alias:
- ALS2CR2,CALS-21,ILPIP,ILPIPA,MGC102916,PAPK,PRO1038
- Gene Description:
- STE20-related kinase adaptor beta
- Omim ID:
- 607333
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. [provided by RefSeq
- Other Designations:
- ILP-interacting protein ILPIPA,STRAD beta,amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2,pseudokinase ALS2CR2