UCP2 (Human) Recombinant Protein (P01)
产品名称： UCP2 (Human) Recombinant Protein (P01)
英文名称： UCP2 (Human) Recombinant Protein (P01)
产品编号： H00007351-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human UCP2 full-length ORF ( AAH11737, 1 a.a. - 309 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MVGFKATDVPPTATVKFLGAGTAACIADLITFPLGTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAACTSREAPF
- Theoretical MW (kDa):
- 59.73
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 7351
- GeneBank Accession#:
- BC011737
- Protein Accession#:
- AAH11737
- Gene Name:
- UCP2
- Gene Alias:
- BMIQ4,SLC25A8,UCPH
- Gene Description:
- uncoupling protein 2 (mitochondrial, proton carrier)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq
- Other Designations:
- uncoupling protein 2,uncoupling protein-2
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Anorexia Nervosa
- Arthritis, Rheumatoid
- Atherosclerosis
- Atherosclerosis
- Body Weight
- Breast cancer
- Breast Neoplasms
- Bulimia
- Calcinosis
- Cardiovascular Diseases
- Carotid Artery Diseases
- Cholangitis, Sclerosing
- Chronic Disease
- Churg-Strauss Syndrome
- Cognition
- Colitis, Ulcerative
- Coronary Artery Disease